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JOHN CABOT UNIVERSITY

COURSE CODE: "PS 375"
COURSE NAME: "Introduction to Neuropsychology"
SEMESTER & YEAR: Spring 2026
SYLLABUS

INSTRUCTOR: Alfredo Spagna
EMAIL: [email protected]
HOURS: MW 1:30 PM 2:45 PM
TOTAL NO. OF CONTACT HOURS: 45
CREDITS: 3
PREREQUISITES: Prerequisites: PS 370 or Permission of the Instructor
OFFICE HOURS:

COURSE DESCRIPTION:
This course provides students with a comprehensive introduction to the methods, findings, and clinical applications of neuropsychology. It explores how lesion-based approaches, complemented by neuroimaging, have shaped current theories of brain organization, and examine how disorders such as aphasia, amnesia, agnosia, and neglect illuminate normal cognition. Students will also gain familiarity with assessment practices and rehabilitation strategies and will consider how advances in technology are reshaping the diagnosis and treatment of neuropsychological disorders.
SUMMARY OF COURSE CONTENT:

This course provides a comprehensive overview of the neuropsychological consequences of major neurological disorders, emphasizing how these conditions illuminate the structure and function of the healthy brain. Students will explore a wide range of disorders (e.g., aphasia, neglect, amnesia) and neurodegenerative diseases such as Alzheimer’s and Parkinson’s. Each topic will be examined through its clinical presentation, underlying neuropathology, and cognitive and behavioral outcomes. Through lectures, case studies, and current research, students will learn how neurological disorders serve as natural experiments for understanding brain systems involved in memory, language, motor control, and executive function.

LEARNING OUTCOMES:
  1. Explain the major assumptions and theoretical frameworks underlying the study of brain–behavior relationships.
  2. Differentiate among major neuropsychological disorders and describe their clinical presentation across early and late stages of disease progression.
  3. Critically evaluate current assessment practices in clinical neuropsychology, identifying strengths, limitations, and potential biases in diagnostic processes.
  4. Propose innovative diagnostic and rehabilitation approaches that integrate emerging technologies and research findings.

 

TEXTBOOK:
NONE
REQUIRED RESERVED READING:
NONE

RECOMMENDED RESERVED READING:
NONE
GRADING POLICY
-ASSESSMENT METHODS:
AssignmentGuidelinesWeight
Offline LearningEach week, a series of video lectures related to the weekly topic will be posted on Moodle. Students are expected to watch the videos on their own and complete quizzes prior to the first class of each week. Students can take quizzes as many times as they need and will only be graded on the final score. 10
Active LearningOne of the goals of this course is to facilitate student engagement through experiential learning. Active engagement will be promoted by: • In-Class Experiment: students will review neuropsychological cases and will work in groups to collect and analyze data, discuss results, and relate them to the scientific literature. • Participation: We will hear from guest speakers online, who will share their research and professional experiences, providing students with the opportunity to learn directly from experts in the field of neuropsychology. 20
Midterm & Final ExamExams will be a mix of multiple choice, fill-in, and short-answer questions. The majority of each test will focus on material covered in the lectures, and the corresponding sections in the textbook.40
Writing AssignmentStudents will analyze gaps/limitations in current assessment or rehabilitation practice for a specific disorder and propose a new approach, critically evaluating the feasibility, benefits, and potential ethical concerns.30

-ASSESSMENT CRITERIA:
AWork of this quality directly addresses the question or problem raised and provides a coherent argument displaying an extensive knowledge of relevant information or content. This type of work demonstrates the ability to critically evaluate concepts and theory and has an element of novelty and originality. There is clear evidence of a significant amount of reading beyond that required for the course.
BThis is highly competent level of performance and directly addresses the question or problem raised.There is a demonstration of some ability to critically evaluatetheory and concepts and relate them to practice. Discussions reflect the student’s own arguments and are not simply a repetition of standard lecture andreference material. The work does not suffer from any major errors or omissions and provides evidence of reading beyond the required assignments.
CThis is an acceptable level of performance and provides answers that are clear but limited, reflecting the information offered in the lectures and reference readings.
DThis level of performances demonstrates that the student lacks a coherent grasp of the material.Important information is omitted and irrelevant points included.In effect, the student has barely done enough to persuade the instructor that s/he should not fail.
FThis work fails to show any knowledge or understanding of the issues raised in the question. Most of the material in the answer is irrelevant.

-ATTENDANCE REQUIREMENTS:
This course provides students with a comprehensive introduction to the methods, findings, and clinical applications of neuropsychology. It explores how lesion-based approaches, complemented by neuroimaging, have shaped current theories of brain organization, and examine how disorders such as aphasia, amnesia, agnosia, and neglect illuminate normal cognition. Students will also gain familiarity with assessment practices and rehabilitation strategies and will consider how advances in technology are reshaping the diagnosis and treatment of neuropsychological disorders.
ACADEMIC HONESTY
As stated in the university catalog, any student who commits an act of academic dishonesty will receive a failing grade on the work in which the dishonesty occurred. In addition, acts of academic dishonesty, irrespective of the weight of the assignment, may result in the student receiving a failing grade in the course. Instances of academic dishonesty will be reported to the Dean of Academic Affairs. A student who is reported twice for academic dishonesty is subject to summary dismissal from the University. In such a case, the Academic Council will then make a recommendation to the President, who will make the final decision.
STUDENTS WITH LEARNING OR OTHER DISABILITIES
John Cabot University does not discriminate on the basis of disability or handicap. Students with approved accommodations must inform their professors at the beginning of the term. Please see the website for the complete policy.

SCHEDULE

Week

Date

Topic

Chapter

Required Journal Readings

Notes

1

Mon Jan 19

Introduction to Course and Content

 

 

Wed Jan 21

Assumptions of Neuropsychology

1

The assumptions on which Neuropsychology stands — Coltheart (2017)

 

2

Mon Jan 26

Nervous System Organization & Methods

3

 

 

Wed Jan 28

3

Mon Feb 2

Principles of Cortical Function

10

Lesion studies in Contemporary Neuroscience — Vaidya et al. (2020)

 

Wed Feb 4

3

Fri Feb 6

Methods in Neuropsychology

28

Can cognitive processes be inferred from neuroimaging data? — Poldrack (2006)

Make-up class for April 6

4

Mon Feb 9

Visual Agnosia, Cortical Blindness, and Aphantasia

13

The Architect Who Lost the Ability to Imagine — Thorudottir et al. (2020)

 

Wed Feb 11

5

Mon Feb 16

Motor Disorders and Apraxia

9

Non-invasive Human Brain Stimulation in Cognitive Neuroscience — Parkin et al. (2015)

 

Wed Feb 18

6

Mon Feb 23

Language Disorders and Aphasia

19

Left-handed musicians show a higher probability of atypical cerebral dominance for language — Villar-Rodríguez et al. (2020)

 

Wed Feb 25

7

Mon Mar 2

Review for Midterm (Covers Weeks 1–6)

Wed Mar 4

Midterm 1, 3, 10, 28, 13, 9, 19

8

Mar 9–13

Spring Break – No Classes

9

Mon Mar 16

Attention and Hemispatial Neglect

22

Quantitative assessment of motor neglect — Toba et al. (2021)

Experiment 2

Wed Mar 18

10

Mon Mar 23

Amnesia and Memory Syndromes

18

Human Lesion Studies in the 21st Century — Adolphs et al. (2020)

 

Wed Mar 25

11

Mon Mar 30

Disorders of Consciousness and Disconnection Syndromes

17 & 22

Perspectives given by structural connectivity — Takemura & Thiebaut de Schotten (2020)

Experiment 3

Wed Apr 1

 

12

Mon Apr 6

Holiday – No Class

see Feb 6

Wed Apr 8

Neuropsychological Assessment

28

Neuropsychological assessment: The not-so-basic basics — Jones et al. (2020)

Experiment 4

13

Mon Apr 13

Neuropsychological Rehabilitation

25

Neuropsychological Tests of the Future — Bilder (2019)

 

Wed Apr 15

Plasticity and Recovery

25

 

 

14

Mon Apr 20

Neurological and Psychiatric Syndromes

26 & 27

Let thy left brain know what thy right brain doeth — Bartolomeo & de Schotten (2016)

 

Wed Apr 22

15

Mon Apr 27

Review for Final Exam

 

May 4–8

Final Exam (Date/time TBD)